The Fox River and Green Bay watersheds have hosted a successful manufacturing and paper industry since the mid-19th century. This activity has propelled the area’s development and shaped its regional identity. However, because of human activity, the Green Bay and Fox River contain high volumes of point-source water contaminants, like polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs). Using models such as the Environmental Kuznets Curve and an exploration of various pollution control methods, this thesis will characterize current and historical patterns in water pollution with respect to industrial activity and intervention methods. The discussion will also explore the effectiveness/ineffectiveness of implemented control measures while using an economic lens to evaluate them from a theory perspective.