Non-suicidal self-injury (NSSI) and suicide are major public health concerns and represent behaviors most practitioners will encounter during their career. Unfortunately, many mental health providers lack confidence in their skills for treating suicidal and/or self-injuring patients. Factors such as concerns about liability, emotional contagion and suicide severity appeared to moderate willingness to treat. There is a lack of research whether these patterns emerge regarding providers’ willingness to treat NSSI, a known risk factor for suicide. This study aimed to explore therapists’ willingness to treat clients with NSSI, Depression, or suicide risk. Participants were emailed through midwestern state licensing lists and asked to answer questions about a hypothetical patient from one of the three conditions. Analyses included chi-square, ANOVA, and regression. Participants showed a lower willingness to treat or accept a patient who has a history of Suicide compared to NSSI or Depression. In addition, both regression models identified significant variables, those being confidence, negative attitudes towards self-harm, and liability concerns that associated with willingness to accept or treat. We also found that the perceived risk of the patient negatvely correlated with willingness to treat. Mental health providers could benefit from increased training about suicide to build their skills and confidence.