Premenstrual dysphoric disorder (PMDD) is an under-researched condition that results in debilitating symptoms for people assigned female at birth (AFAB). It is characterized by extreme mental and physical symptoms that occur in the two weeks before a person’s menstrual cycle, such as depression, fits of rage, and joint pain. Researchers have been unable to narrow down a cause for this disorder, although it’s suspected to be due to abnormal hormonal activity. PMDD has been found to be more prevalent in Latin American countries, prompting a study that synthesizes prior peer-reviewed literature about this disorder in Latin America. This study seeks to educate its audience on PMDD, evaluate the impact of PMDD in Latin America, and draw implications about AFAB healthcare there. It is valuable because it could inspire future studies regarding an under researched medical condition that impacts AFAB people, a group that already experiences barriers to healthcare. The findings indicate that PMDD may be more prevalent in some areas of Latin America than in the United States due to unique socioeconomic factors, and that not all Latin American countries view the disorder the same.